V2 software is designed for the Teensy LC and APA102C LEDs, the hardware used in the Game Frame redesign launched this year. Neopixels are incompatible with the IR Remote control, since they tie up the system interrupts, but if you want to try it out you can just change the LED type from APA102 to WS2812.
I used the version of Entropy installed with Teeensyduino.