Hi Andrew. The best place to start is going to be the NeoPixel library from Adafruit. It drives the LEDs in Game Frame, and the examples in the library will show you how to address individual lights. From there, the real fun will be figuring out the input engineering. 256 buttons is way beyond the limited Arduino pins, so you’re looking at additional hardware. I’m sure others can specific chip suggestions, but I know old school computer keyboards employ a switch matrix to solve the same problem.